1DNU

STRUCTURAL ANALYSES OF HUMAN MYELOPEROXIDASE-THIOCYANATE COMPLEX

Summary for 1DNU

• Entry DOI: 10.2210/pdb1dnu/pdb
• Related: 1CXP 1D2V 1D5L 1D7W 1DNW 1MHL 1MYP
• Descriptor: MYELOPEROXIDASE, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, THIOCYANATE ION, ... (10 entities in total)
• Functional Keywords: oxidoreductase, peroxidase, inhibitor complex thiocyanate, halide peroxidation, neutrophil
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 135467.79

Authors

Blair-Johnson, M.,Fiedler, T.J.,Fenna, R.E. (deposition date: 1999-12-16, release date: 2001-12-21, Last modification date: 2020-07-29)

• Primary citation: Blair-Johnson, M.,Fiedler, T.,Fenna, R.; Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.; Biochemistry, 40:13990-13997, 2001; PubMed: 11705390; DOI: 10.1021/bi0111808

Experimental method

X-RAY DIFFRACTION (1.85 Å)