1D6W

STRUCTURE OF THROMBIN COMPLEXED WITH SELECTIVE NON-ELECTROPHILIC INHIBITORS HAVING CYCLOHEXYL MOIETIES AT P1

Summary for 1D6W

• Entry DOI: 10.2210/pdb1d6w/pdb
• Descriptor: THROMBIN, DECAPEPTIDE INHIBITOR, SODIUM ION, ... (5 entities in total)
• Functional Keywords: hydrolase, thrombin, thrombin inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734; Secreted: P28511
• Total number of polymer chains: 2
• Total formula weight: 35030.97

Authors

Mochalkin, I.,Tulinsky, A. (deposition date: 1999-10-15, release date: 2000-10-25, Last modification date: 2017-10-04)

• Primary citation: Krishnan, R.,Mochalkin, I.,Arni, R.,Tulinsky, A.; Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1.; Acta Crystallogr.,Sect.D, 56:294-303, 2000; PubMed: 10713516; DOI: 10.1107/S0907444900000068

Experimental method

X-RAY DIFFRACTION (2 Å)