1CVW
Crystal structure of active site-inhibited human coagulation factor VIIA (DES-GLA)
Summary for 1CVW
Entry DOI | 10.2210/pdb1cvw/pdb |
Related | 1DAN |
Related PRD ID | PRD_000287 |
Descriptor | COAGULATION FACTOR VIIA (LIGHT CHAIN) (DES-GLA), COAGULATION FACTOR VIIA (HEAVY CHAIN) (DES-GLA), N-{[5-(dimethylamino)naphthalen-1-yl]sulfonyl}-L-alpha-glutamyl-N-[(2S,3S)-6-carbamimidamido-1-chloro-2-hydroxyhexan-3-yl]glycinamide, ... (5 entities in total) |
Functional Keywords | blood coagulation, factor viia, serine protease, egf, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P08709 P08709 |
Total number of polymer chains | 2 |
Total formula weight | 34802.30 |
Authors | Kemball-Cook, G.,Johnson, D.J.D.,Tuddenham, E.G.D.,Harlos, K. (deposition date: 1999-08-24, release date: 1999-08-31, Last modification date: 2013-02-27) |
Primary citation | Kemball-Cook, G.,Johnson, D.J.,Tuddenham, E.G.,Harlos, K. Crystal structure of active site-inhibited human coagulation factor VIIa (des-Gla). J.Struct.Biol., 127:213-223, 1999 Cited by PubMed: 10544046DOI: 10.1006/jsbi.1999.4158 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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