1CTE
CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
Summary for 1CTE
Entry DOI | 10.2210/pdb1cte/pdb |
Descriptor | CATHEPSIN B, 2-PYRIDINETHIOL (3 entities in total) |
Functional Keywords | thiol protease |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Lysosome: P00787 |
Total number of polymer chains | 2 |
Total formula weight | 55694.03 |
Authors | Huber, C.P.,Jia, Z. (deposition date: 1995-05-03, release date: 1995-07-31, Last modification date: 2024-06-05) |
Primary citation | Jia, Z.,Hasnain, S.,Hirama, T.,Lee, X.,Mort, J.S.,To, R.,Huber, C.P. Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design. J.Biol.Chem., 270:5527-5533, 1995 Cited by PubMed: 7890671DOI: 10.1074/jbc.270.10.5527 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report