1CNW

SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS

Summary for 1CNW

Entry DOI	10.2210/pdb1cnw/pdb
Descriptor	CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywords	lyase (oxo-acid)
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00918
Total number of polymer chains	1
Total formula weight	29943.50
Authors	Boriack, P.A.,Christianson, D.W. (deposition date: 1995-07-21, release date: 1995-11-14, Last modification date: 2024-02-07)
Primary citation	Boriack, P.A.,Christianson, D.W.,Kingery-Wood, J.,Whitesides, G.M. Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38:2286-2291, 1995 Cited by PubMed: 7608893 DOI: 10.1021/jm00013a004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation