1CKZ

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR: SOLUTION STRUCTURES OF PEPTIDES BASED ON THE PHE508 REGION, THE MOST COMMON SITE OF DISEASE-CAUSING DELTA-F508 MUTATION

Summary for 1CKZ

Entry DOI	10.2210/pdb1ckz/pdb
Related	1CKW 1CKX 1CKY
NMR Information	BMRB: 4598
Descriptor	PROTEIN (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR)) (1 entity in total)
Functional Keywords	cystic fibrosis, peptides, metal transport
Cellular location	Early endosome membrane; Multi-pass membrane protein (By similarity): Q00555
Total number of polymer chains	1
Total formula weight	2907.35
Authors	Massiah, M.A.,Ko, Y.H.,Pedersen, P.L.,Mildvan, A.S. (deposition date: 1999-04-26, release date: 1999-05-04, Last modification date: 2023-12-27)
Primary citation	Massiah, M.A.,Ko, Y.H.,Pedersen, P.L.,Mildvan, A.S. Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation. Biochemistry, 38:7453-7461, 1999 Cited by PubMed: 10360942 DOI: 10.1021/bi9903603 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation