1CKT

CRYSTAL STRUCTURE OF HMG1 DOMAIN A BOUND TO A CISPLATIN-MODIFIED DNA DUPLEX

Summary for 1CKT

• Entry DOI: 10.2210/pdb1ckt/pdb
• Descriptor: DNA (5'-D(*CP*CP*(5IU)P*CP*TP*CP*TP*GP*GP*AP*CP*CP*TP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*GP*TP*CP*CP*AP*GP*AP*GP*AP*GP*G)-3'), HIGH MOBILITY GROUP 1 PROTEIN, ... (5 entities in total)
• Functional Keywords: high-mobility group domain, bent dna, protein-drug-dna complex, gene regulation-dna complex, gene regulation/dna
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Nucleus: P63159
• Total number of polymer chains: 3
• Total formula weight: 18708.06

Authors

Ohndorf, U.-M.,Rould, M.A.,Pabo, C.O.,Lippard, S.J. (deposition date: 1999-04-23, release date: 1999-06-30, Last modification date: 2023-12-27)

• Primary citation: Ohndorf, U.M.,Rould, M.A.,He, Q.,Pabo, C.O.,Lippard, S.J.; Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins.; Nature, 399:708-712, 1999; PubMed: 10385126; DOI: 10.1038/21460

Experimental method

X-RAY DIFFRACTION (2.5 Å)