1CIL
THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS
Summary for 1CIL
Entry DOI | 10.2210/pdb1cil/pdb |
Descriptor | CARBONIC ANHYDRASE II, ZINC ION, (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, ... (4 entities in total) |
Functional Keywords | lyase(oxo-acid) |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29547.71 |
Authors | Smith, G.M.,Alexander, R.S.,Christianson, D.W.,Mckeever, B.M.,Ponticello, G.S.,Springer, J.P.,Randall, W.C.,Baldwin, J.J.,Habecker, C.N. (deposition date: 1993-10-20, release date: 1994-01-31, Last modification date: 2024-02-07) |
Primary citation | Smith, G.M.,Alexander, R.S.,Christianson, D.W.,McKeever, B.M.,Ponticello, G.S.,Springer, J.P.,Randall, W.C.,Baldwin, J.J.,Habecker, C.N. Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors. Protein Sci., 3:118-125, 1994 Cited by PubMed: 8142888PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report