1CCU

STRUCTURE-ASSISTED REDESIGN OF A PROTEIN-ZINC BINDING SITE WITH FEMTOMOLAR AFFINITY

Summary for 1CCU

Entry DOI	10.2210/pdb1ccu/pdb
Descriptor	CARBONIC ANHYDRASE II, ZINC ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	lyase (oxo-acid)
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29356.38
Authors	Ippolito, J.A.,Christianson, D.W. (deposition date: 1994-12-09, release date: 1995-02-07, Last modification date: 2024-02-07)
Primary citation	Ippolito, J.A.,Baird Jr., T.T.,McGee, S.A.,Christianson, D.W.,Fierke, C.A. Structure-assisted redesign of a protein-zinc-binding site with femtomolar affinity. Proc.Natl.Acad.Sci.USA, 92:5017-5021, 1995 Cited by PubMed: 7761440 DOI: 10.1073/pnas.92.11.5017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation