1C4V
SELECTIVE NON ELECTROPHILIC THROMBIN INHIBITORS WITH CYCLOHEXYL MOIETIES.
Summary for 1C4V
Entry DOI | 10.2210/pdb1c4v/pdb |
Descriptor | THROMBIN:SHORT CHAIN, THROMBIN:LONG CHAIN, HIRUGEN, ... (6 entities in total) |
Functional Keywords | complex (serine protease-inhibitor), hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 |
Total number of polymer chains | 3 |
Total formula weight | 36266.28 |
Authors | Krishnan, R.,Mochalkin, I.,Arni, R.K.,Tulinsky, A. (deposition date: 1999-09-25, release date: 2000-09-27, Last modification date: 2023-11-15) |
Primary citation | Krishnan, R.,Mochalkin, I.,Arni, R.,Tulinsky, A. Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1. Acta Crystallogr.,Sect.D, 56:294-303, 2000 Cited by PubMed: 10713516DOI: 10.1107/S0907444900000068 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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