1C07
STRUCTURE OF THE THIRD EPS15 HOMOLOGY DOMAIN OF HUMAN EPS15
Summary for 1C07
| Entry DOI | 10.2210/pdb1c07/pdb |
| Descriptor | PROTEIN (EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 15), CALCIUM ION (2 entities in total) |
| Functional Keywords | calcium binding, signaling domain, npf binding, fw binding, ef-hand, eh domain, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm. Isoform 2: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side: P42566 |
| Total number of polymer chains | 1 |
| Total formula weight | 10666.46 |
| Authors | Enmon, J.L.,De Beer, T.,Overduin, M. (deposition date: 1999-07-14, release date: 2000-07-19, Last modification date: 2022-02-16) |
| Primary citation | Enmon, J.L.,de Beer, T.,Overduin, M. Solution structure of Eps15's third EH domain reveals coincident Phe-Trp and Asn-Pro-Phe binding sites. Biochemistry, 39:4309-4319, 2000 Cited by PubMed: 10757979DOI: 10.1021/bi9927383 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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