1BWS

CRYSTAL STRUCTURE OF GDP-4-KETO-6-DEOXY-D-MANNOSE EPIMERASE/REDUCTASE FROM ESCHERICHIA COLI A KEY ENZYME IN THE BIOSYNTHESIS OF GDP-L-FUCOSE

Summary for 1BWS

Entry DOI	10.2210/pdb1bws/pdb
Descriptor	PROTEIN (GDP-4-KETO-6-DEOXY-D-MANNOSE EPIMERASE/REDUCTASE), NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	epimerase/reductase, gdp-l-fucose biosynthesis, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	36918.50
Authors	Rizzi, M.,Tonetti, M.,Flora, A.D.,Bolognesi, M. (deposition date: 1998-09-25, release date: 1999-01-13, Last modification date: 2024-02-07)
Primary citation	Rizzi, M.,Tonetti, M.,Vigevani, P.,Sturla, L.,Bisso, A.,Flora, A.D.,Bordo, D.,Bolognesi, M. GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily. Structure, 6:1453-1465, 1998 Cited by PubMed: 9817848 DOI: 10.1016/S0969-2126(98)00144-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation