1BTK
PH DOMAIN AND BTK MOTIF FROM BRUTON'S TYROSINE KINASE MUTANT R28C
Summary for 1BTK
| Entry DOI | 10.2210/pdb1btk/pdb |
| Descriptor | BRUTON'S TYROSINE KINASE, ZINC ION, SODIUM ION, ... (4 entities in total) |
| Functional Keywords | transferase, ph domain, btk motif, zinc binding, x-linked agammaglobulinemia, tyrosine-protein kinase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm (By similarity): Q06187 |
| Total number of polymer chains | 2 |
| Total formula weight | 40034.72 |
| Authors | Hyvonen, M.,Saraste, M. (deposition date: 1997-07-01, release date: 1997-09-17, Last modification date: 2024-02-07) |
| Primary citation | Hyvonen, M.,Saraste, M. Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia. EMBO J., 16:3396-3404, 1997 Cited by PubMed: 9218782DOI: 10.1093/emboj/16.12.3396 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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