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1BB0

THROMBIN INHIBITORS WITH RIGID TRIPEPTIDYL ALDEHYDES

Summary for 1BB0
Entry DOI10.2210/pdb1bb0/pdb
Related PRD IDPRD_000324
DescriptorTHROMBIN, HIRUGEN, SODIUM ION, ... (6 entities in total)
Functional Keywordshydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHirudo medicinalis (medicinal leech)
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Cellular locationSecreted, extracellular space: P00734 P00734
Total number of polymer chains3
Total formula weight35990.93
Authors
Krishnan, R.,Zhang, E.,Hakansson, K.,Arni, R.K.,Tulinsky, A.,Lim-Wilby, M.S.L.,Levy, O.E.,Semple, J.E.,Brunck, T.K. (deposition date: 1998-04-28, release date: 1999-04-27, Last modification date: 2023-08-02)
Primary citationKrishnan, R.,Zhang, E.,Hakansson, K.,Arni, R.K.,Tulinsky, A.,Lim-Wilby, M.S.,Levy, O.E.,Semple, J.E.,Brunck, T.K.
Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.
Biochemistry, 37:12094-12103, 1998
Cited by
PubMed: 9724521
DOI: 10.1021/bi980840e
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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