1B9V
NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN TEH ACTIVE SITE
Summary for 1B9V
Entry DOI | 10.2210/pdb1b9v/pdb |
Descriptor | PROTEIN (NEURAMINIDASE), 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | influenza, neuraminidase, sialidase, b/lee/40, hydrolase |
Biological source | Influenza B virus (B/Lee/40) |
Cellular location | Virion membrane (By similarity): P03474 |
Total number of polymer chains | 1 |
Total formula weight | 44112.12 |
Authors | Finley, J.B.,Atigadda, V.R.,Duarte, F.,Zahao, J.J.,Brouillette, W.J.,Air, G.M.,Luo, M. (deposition date: 1999-02-15, release date: 1999-02-27, Last modification date: 2023-08-09) |
Primary citation | Finley, J.B.,Atigadda, V.R.,Duarte, F.,Zhao, J.J.,Brouillette, W.J.,Air, G.M.,Luo, M. Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site. J.Mol.Biol., 293:1107-1119, 1999 Cited by PubMed: 10547289DOI: 10.1006/jmbi.1999.3180 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
Download full validation report