1AXB

TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI INHIBITED WITH AN ACYLATION TRANSITION STATE ANALOG

Summary for 1AXB

Entry DOI	10.2210/pdb1axb/pdb
Descriptor	TEM-1 BETA LACTAMASE, [[N-(BENZYLOXYCARBONYL)AMINO]METHYL]PHOSPHATE (3 entities in total)
Functional Keywords	hydrolase, antibiotic resistance, beta-lactamase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	29229.25
Authors	Maveyraud, L.,Pratt, R.F.,Samama, J.P. (deposition date: 1997-10-14, release date: 1998-10-28, Last modification date: 2011-07-13)
Primary citation	Maveyraud, L.,Pratt, R.F.,Samama, J.P. Crystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases. Biochemistry, 37:2622-2628, 1998 Cited by PubMed: 9485412 DOI: 10.1021/bi972501b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation