1AEV

INTRODUCTION OF NOVEL SUBSTRATE OXIDATION INTO CYTOCHROME C PEROXIDASE BY CAVITY COMPLEMENTATION: OXIDATION OF 2-AMINOTHIAZOLE AND COVALENT MODIFICATION OF THE ENZYME (2-AMINOTHIAZOLE)

Summary for 1AEV

Entry DOI	10.2210/pdb1aev/pdb
Descriptor	CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2-AMINOTHIAZOLE, ... (4 entities in total)
Functional Keywords	oxidoreductase, peroxidase, transit peptide
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Mitochondrion matrix: P00431
Total number of polymer chains	1
Total formula weight	34175.87
Authors	Musah, R.A.,Fitzgerald, M.M.,Jensen, G.M.,Mcree, D.E.,Goodin, D.B. (deposition date: 1997-02-25, release date: 1997-09-04, Last modification date: 2023-08-02)
Primary citation	Musah, R.A.,Goodin, D.B. Introduction of novel substrate oxidation into cytochrome c peroxidase by cavity complementation: oxidation of 2-aminothiazole and covalent modification of the enzyme. Biochemistry, 36:11665-11674, 1997 Cited by PubMed: 9305956 DOI: 10.1021/bi9708038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation