1AEO

SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (2-AMINOPYRIDINE)

Summary for 1AEO

Entry DOI	10.2210/pdb1aeo/pdb
Descriptor	CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2-AMINOPYRIDINE, ... (4 entities in total)
Functional Keywords	oxidoreductase, peroxidase, transit peptide
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Mitochondrion matrix: P00431
Total number of polymer chains	1
Total formula weight	34170.85
Authors	Musah, R.A.,Jensen, G.M.,Bunte, S.W.,Rosenfeld, R.,Mcree, D.E.,Goodin, D.B. (deposition date: 1997-02-25, release date: 1997-09-04, Last modification date: 2023-08-02)
Primary citation	Musah, R.A.,Jensen, G.M.,Bunte, S.W.,Rosenfeld, R.J.,Goodin, D.B. Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein. J.Mol.Biol., 315:845-857, 2002 Cited by PubMed: 11812152 DOI: 10.1006/jmbi.2001.5287 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation