1AE5
HUMAN HEPARIN BINDING PROTEIN
Summary for 1AE5
| Entry DOI | 10.2210/pdb1ae5/pdb |
| Descriptor | HEPARIN BINDING PROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
| Functional Keywords | serine protease homolog, endotoxin binding, heparin binding, inflammation, antibacterial, cap37, azurocidin, glycosylated protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 24744.89 |
| Authors | Iversen, L.F.,Kastrup, J.S.,Bjorn, S.E.,Rasmussen, P.B.,Wiberg, F.C.,Flodgaard, H.J.,Larsen, I.K. (deposition date: 1997-03-05, release date: 1998-03-11, Last modification date: 2024-12-25) |
| Primary citation | Iversen, L.F.,Kastrup, J.S.,Bjorn, S.E.,Rasmussen, P.B.,Wiberg, F.C.,Flodgaard, H.J.,Larsen, I.K. Structure of HBP, a multifunctional protein with a serine proteinase fold. Nat.Struct.Biol., 4:265-268, 1997 Cited by PubMed Abstract: The structure of human heparin binding protein reveals that the serine proteinase fold has been used as a scaffold for a multifunctional protein with antibacterial activity, monocyte and t-cell activating properties and endotoxin and heparin binding capacity. PubMed: 9095193DOI: 10.1038/nsb0497-265 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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