1ADF
CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE ADENINE DINUCLEOTIDE (TAD), THE ACTIVE ANABOLITE OF THE ANTITUMOR AGENT TIAZOFURIN
Summary for 1ADF
Entry DOI | 10.2210/pdb1adf/pdb |
Descriptor | ALCOHOL DEHYDROGENASE, ZINC ION, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | oxidoreductase(nad(a)-choh(d)) |
Biological source | Equus caballus (horse) |
Cellular location | Cytoplasm: P00327 |
Total number of polymer chains | 1 |
Total formula weight | 40651.57 |
Authors | Li, H.,Hallows, W.A.,Punzi, J.S.,Marquez, V.E.,Carrell, H.L.,Pankiewicz, K.W.,Watanabe, K.A.,Goldstein, B.M. (deposition date: 1993-10-18, release date: 1994-01-31, Last modification date: 2024-02-07) |
Primary citation | Li, H.,Hallows, W.H.,Punzi, J.S.,Marquez, V.E.,Carrell, H.L.,Pankiewicz, K.W.,Watanabe, K.A.,Goldstein, B.M. Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin. Biochemistry, 33:23-32, 1994 Cited by PubMed: 8286346DOI: 10.1021/bi00167a004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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