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1A5W

ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3

Summary for 1A5W
Entry DOI10.2210/pdb1a5w/pdb
DescriptorINTEGRASE, 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID (3 entities in total)
Functional Keywordshydrolase, endonuclease, hiv-1 integrase inhibitor
Biological sourceRous sarcoma virus (strain Schmidt-Ruppin)
Cellular locationMatrix protein p19: Virion (Potential). Capsid protein p27: Virion (Potential). Nucleocapsid protein p12: Virion (Potential): P03354
Total number of polymer chains1
Total formula weight17760.27
Authors
Lubkowski, J.,Yang, F.,Alexandratos, J.,Wlodawer, A. (deposition date: 1998-02-18, release date: 1998-05-27, Last modification date: 2023-08-02)
Primary citationLubkowski, J.,Yang, F.,Alexandratos, J.,Wlodawer, A.,Zhao, H.,Burke Jr., T.R.,Neamati, N.,Pommier, Y.,Merkel, G.,Skalka, A.M.
Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95:4831-4836, 1998
Cited by
PubMed: 9560188
DOI: 10.1073/pnas.95.9.4831
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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