1A5I
CATALYTIC DOMAIN OF VAMPIRE BAT (DESMODUS ROTUNDUS) SALIVA PLASMINOGEN ACTIVATOR IN COMPLEX WITH EGR-CMK (GLU-GLY-ARG CHLOROMETHYL KETONE)
Summary for 1A5I
| Entry DOI | 10.2210/pdb1a5i/pdb |
| Related PRD ID | PRD_000288 |
| Descriptor | PLASMINOGEN ACTIVATOR, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide (3 entities in total) |
| Functional Keywords | serine protease, fibrinolytic enzymes, plasminogen activators, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Desmodus rotundus (common vampire bat) |
| Cellular location | Secreted: P98119 |
| Total number of polymer chains | 1 |
| Total formula weight | 30112.46 |
| Authors | Renatus, M.,Stubbs, M.T.,Bode, W. (deposition date: 1998-02-17, release date: 1999-03-23, Last modification date: 2023-08-02) |
| Primary citation | Renatus, M.,Stubbs, M.T.,Huber, R.,Bringmann, P.,Donner, P.,Schleuning, W.D.,Bode, W. Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage. Biochemistry, 36:13483-13493, 1997 Cited by PubMed: 9354616DOI: 10.1021/bi971129x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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