185D

SEQUENCE SPECIFICITY OF QUINOXALINE ANTIBIOTICS. 1. SOLUTION STRUCTURE OF A 1:1 COMPLEX BETWEEN TRIOSTIN A AND [D(GACGTC)]2 AND COMPARISON WITH THE SOLUTION STRUCTURE OF THE [N-MECYS3, N-MECYS7]TANDEM-[D(GATATC)]2 COMPLEX

185D の概要

• エントリーDOI: 10.2210/pdb185d/pdb
• 関連するPDBエントリー: 193D 1PFE 1VS2 1XVK 1XVN 1XVR 2ADW 2DA8 3GO3
• 関連するBIRD辞書のPRD_ID: PRD_000488
• 分子名称: TRIOSTIN A, DNA (5'-D(*GP*AP*CP*GP*TP*C)-3'), 2-CARBOXYQUINOXALINE (3 entities in total)
• 機能のキーワード: bisintercalator, depsipeptide, quinoxaline, antibiotic, antitumor, dna-antibiotic complex, dna/antibiotic
• 由来する生物種: STREPTOMYCINEAE
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 4761.73

構造登録者

Addess, K.J.,Feigon, J. (登録日: 1994-08-10, 公開日: 1995-02-07, 最終更新日: 2017-11-01)

• 主引用文献: Addess, K.J.,Feigon, J.; Sequence Specificity of Quinoxaline Antibiotics. 1. Solution Structure of a 1:1 Complex between Triostin a and [D(Gacgtc)]2 and Comparison with the Solution Structure of the [N-Mecys3,N-Mecys7]Tandem-[D(Gatatc)]2 Complex.; Biochemistry, 33:12386-, 1994; PubMed: 7918461; DOI: 10.1021/BI00207A005

実験手法

SOLUTION NMR