16PK

PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA BRUCEI BISUBSTRATE ANALOG

Summary for 16PK

Entry DOI	10.2210/pdb16pk/pdb
Descriptor	3-PHOSPHOGLYCERATE KINASE, 1,1,5,5-TETRAFLUOROPHOSPHOPENTYLPHOSPHONIC ACID ADENYLATE ESTER, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	kinase, phosphoglycerate, ternary complex, glycolysis, transferase, bisubstrate, analog
Biological source	Trypanosoma brucei
Cellular location	Glycosome: P07378
Total number of polymer chains	1
Total formula weight	45571.56
Authors	Bernstein, B.E.,Bressi, J.,Blackburn, M.,Gelb, M.,Hol, W.G.J. (deposition date: 1998-05-18, release date: 1998-11-25, Last modification date: 2023-08-02)
Primary citation	Bernstein, B.E.,Williams, D.M.,Bressi, J.C.,Kuhn, P.,Gelb, M.H.,Blackburn, G.M.,Hol, W.G. A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from Trypanosoma brucei. J.Mol.Biol., 279:1137-1148, 1998 Cited by PubMed: 9642090 DOI: 10.1006/jmbi.1998.1835 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation