13FL

Structure of FabS1CE2_P2a in complex with the N-terminal domain of PD-L1

13FL の概要

• エントリーDOI: 10.2210/pdb13fl/pdb
• 関連するPDBエントリー: 13DS 13DT
• 分子名称: FabS1CE2_P2a heavy chain, FabS1CE2_P2a light chain (Trastuzumab Fab Light Chain), Programmed cell death 1 ligand 1, ... (7 entities in total)
• 機能のキーワード: high-affinity binding, immune suppression, tumour growth suppressor, cell signalling, pd-l1, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 62503.33

構造登録者

Mallette, E.,Singer, A.U.,Blazer, L.L.,Adams, J.J.,Suits, M.D.L.,Sidhu, S.S. (登録日: 2026-05-04, 公開日: 2026-06-03)

• 主引用文献: Mallette, E.,Blazer, L.L.,Hokanson, C.A.,Chen, C.,Perez, J.G.,Pavkenco, A.,Ploder, L.,Singer, A.U.,Suits, M.D.L.,Adams, J.J.,Sidhu, S.S.; A Strategy for Modular Assembly of Tetravalent Multispecific Antibodies; To Be Published,

実験手法

X-RAY DIFFRACTION (2.22 Å)