134D

SOLUTION STRUCTURE OF A PURINE(DOT)PURINE(DOT)PYRIMIDINE DNA TRIPLEX CONTAINING G(DOT)GC AND T(DOT)AT TRIPLES

134D の概要

• エントリーDOI: 10.2210/pdb134d/pdb
• 関連するPDBエントリー: 135D 136D
• 分子名称: DNA TRIPLEX (1 entity in total)
• 機能のキーワード: dna, triplex
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9552.12

構造登録者

Patel, D.J.,Radhakrishnan, I. (登録日: 1993-08-30, 公開日: 1994-04-30, 最終更新日: 2024-04-10)

主引用文献

Radhakrishnan, I.,Patel, D.J.
Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Structure, 1:135-152, 1993

PubMed Abstract: Oligonucleotide-directed triple helix formation allows sequence specific recognition of double helical DNA. This powerful approach has been used to inhibit gene transcription in vitro and to mediate single site specific cleavage of a human chromosome.

PubMed: 8069626
DOI: 10.1016/0969-2126(93)90028-F

実験手法

SOLUTION NMR