11TU

Crystal structure of alpha/beta-hydrolase macrolide esterase EstT from Bacillus cereus (S102A mutant) in complex with linearized tylvalosin

This is a non-PDB format compatible entry.

Summary for 11TU

• Entry DOI: 10.2210/pdb11tu/pdb
• Descriptor: alpha/beta-hydrolase macrolide esterase EstT, linearized tylvalosin (3 entities in total)
• Functional Keywords: alpha/beta-hydrolase, esterase, macrolide resistance, hydrolase
• Biological source: Bacillus cereus
• Total number of polymer chains: 1
• Total formula weight: 32569.92

Authors

Kelly, E.T.R.,Blanchet, J.,Berghuis, A.M. (deposition date: 2026-03-12, release date: 2026-04-08)

• Primary citation: Kelly, E.T.R.,Myziuk, I.,Hemmings, M.Z.,Mulla, Z.,Blanchet, J.,Ruzzini, A.,Berghuis, A.M.; Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases; Biorxiv, 2026; DOI: 10.64898/2026.03.24.713787

Experimental method

X-RAY DIFFRACTION (1.7 Å)