117E
THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS
Summary for 117E
Entry DOI | 10.2210/pdb117e/pdb |
Descriptor | PROTEIN (INORGANIC PYROPHOSPHATASE), MANGANESE (II) ION, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | enzyme mechanism, iorganic pyrophosphatase, mutan structures, 2-metal ion mechanism, hydrolase |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Cellular location | Cytoplasm: P00817 |
Total number of polymer chains | 2 |
Total formula weight | 65203.21 |
Authors | Tuominen, V.,Heikinheimo, P.,Kajander, T.,Torkkel, T.,Hyytia, T.,Kapyla, J.,Lahti, R.,Cooperman, B.S.,Goldman, A. (deposition date: 1998-09-15, release date: 1998-12-23, Last modification date: 2023-08-09) |
Primary citation | Tuominen, V.,Heikinheimo, P.,Kajander, T.,Torkkel, T.,Hyytia, T.,Kapyla, J.,Lahti, R.,Cooperman, B.S.,Goldman, A. The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications. J.Mol.Biol., 284:1565-1580, 1998 Cited by PubMed: 9878371DOI: 10.1006/jmbi.1998.2266 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report