10MH

TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND HEMIMETHYLATED DNA CONTAINING 5,6-DIHYDRO-5-AZACYTOSINE AT THE TARGET

10MH の概要

• エントリーDOI: 10.2210/pdb10mh/pdb
• 分子名称: DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*5NCP*GP*CP*AP*TP*GP*G)-3'), PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), ... (5 entities in total)
• 機能のキーワード: transferase, methyltransferase, restriction system, complex (methyltransferase- dna), transferase-dna complex, transferase/dna
• 由来する生物種: Haemophilus haemolyticus
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44768.42

構造登録者

Sheikhnejad, G.,Brank, A.,Christman, J.K.,Goddard, A.,Alvarez, E.,Ford Junior, H.,Marquez, V.E.,Marasco, C.J.,Sufrin, J.R.,O'Gara, M.,Cheng, X. (登録日: 1998-08-10, 公開日: 1999-02-09, 最終更新日: 2023-08-09)

• 主引用文献: Sheikhnejad, G.,Brank, A.,Christman, J.K.,Goddard, A.,Alvarez, E.,Ford Jr., H.,Marquez, V.E.,Marasco, C.J.,Sufrin, J.R.,O'gara, M.,Cheng, X.; Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.; J.Mol.Biol., 285:2021-2034, 1999; PubMed: 9925782; DOI: 10.1006/jmbi.1998.2426

実験手法

X-RAY DIFFRACTION (2.55 Å)