109D

VARIABILITY IN DNA MINOR GROOVE WIDTH RECOGNISED BY LIGAND BINDING: THE CRYSTAL STRUCTURE OF A BIS-BENZIMIDAZOLE COMPOUND BOUND TO THE DNA DUPLEX D(CGCGAATTCGCG)2

Summary for 109D

DescriptorDNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 5-(2-IMIDAZOLINYL)-2-[2-(4-HYDROXYPHENYL)-5-BENZIMIDAZOLYL]BENZIMIDAZOLE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsb-dna, double helix, complexed with drug, dna
Total number of polymer chains2
Total molecular weight7747.53
Authors
Czarny, A.,Boykin, D.W.,Wood, A.A.,Nunn, C.M.,Neidle, S.,Zhao, M.,Wilson, W.D. (deposition date: 1995-02-15, release date: 1995-05-08, Last modification date: 2011-07-13)
Primary citation
Wood, A.A.,Nunn, C.M.,Czarny, A.,Boykin, D.W.,Neidle, S.
Variability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2.
Nucleic Acids Res., 23:3678-3684, 1995
PubMed: 7478996 (PDB entries with the same primary citation)
DOI: 10.1093/nar/23.18.3678
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRSRZ outliers60MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution