102D

SEQUENCE-DEPENDENT DRUG BINDING TO THE MINOR GROOVE OF DNA: THE CRYSTAL STRUCTURE OF THE DNA DODECAMER D(CGCAAATTTGCG)2 COMPLEXED WITH PROPAMIDINE

102D の概要

• エントリーDOI: 10.2210/pdb102d/pdb
• 分子名称: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3'), 1,3-BIS(AMIDINOPHENOXY)PROPANE (3 entities in total)
• 機能のキーワード: b-dna, double helix, complexed with drug, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7637.17

構造登録者

Nunn, C.M.,Neidle, S. (登録日: 1994-12-15, 公開日: 1995-02-07, 最終更新日: 2024-02-07)

• 主引用文献: Nunn, C.M.,Neidle, S.; Sequence-dependent drug binding to the minor groove of DNA: crystal structure of the DNA dodecamer d(CGCAAATTTGCG)2 complexed with propamidine.; J.Med.Chem., 38:2317-2325, 1995; PubMed: 7608897; DOI: 10.1021/jm00013a008

実験手法

X-RAY DIFFRACTION (2.2 Å)