7K6W

Structure of the PTP-like myo-inositol phosphatase from Desulfovibrio magneticus in complex with myo-inositol hexakisphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Myo-inositol phosphohydrolase	polymer	310	32921.1	4	UniProt (C4XPJ9) Pfam (PF14566) In PDB	Desulfovibrio magneticus
2	A, B, C, D	INOSITOL HEXAKISPHOSPHATE	non-polymer		660.0	4	Chemie (IHP)
3	A, B, C, D	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
4	A, B, C, D	ACETATE ION	non-polymer		59.0	13	Chemie (ACT)
5		water	water		18.0	463	Chemie (HOH)

Sequence modifications

A, B, C, D: 43 - 331 (UniProt: C4XPJ9)

PDB	External Database	Details
Met 22	-	initiating methionine
Gly 23	-	expression tag
Ser 24	-	expression tag
Ser 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
Ser 32	-	expression tag
Ser 33	-	expression tag
Gly 34	-	expression tag
Leu 35	-	expression tag
Val 36	-	expression tag
Pro 37	-	expression tag
Arg 38	-	expression tag
Gly 39	-	expression tag
Ser 40	-	expression tag
His 41	-	expression tag
Met 42	-	expression tag
Ser 241	Cys 241	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	131684.5
Non-Polymers*	Number of molecules	21
	Total formula weight	3787.6
All*	Total formula weight	135472.1

*Water molecules are not included.