6FZG
PPAR gamma mutant complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peroxisome proliferator-activated receptor gamma | polymer | 276 | 31598.8 | 1 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | A | (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid | non-polymer | 495.6 | 1 | Chemie (EDK) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A: 231 - 505 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Met 230 | - | initiating methionine |
| Met 290 | Ile 262 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31598.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 531.0 | |
| All* | Total formula weight | 32129.8 |
