4H10
Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Aryl hydrocarbon receptor nuclear translocator-like protein 1 | polymer | 73 | 8693.2 | 1 | UniProt (O00327) Pfam (PF00010) In PDB | Homo sapiens (human) | Basic-helix-loop-helix-PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5, bHLHe5, Member of PAS protein 3, PAS domain-containing protein 3, bHLH-PAS protein JAP3 |
2 | B | Circadian locomoter output cycles protein kaput | polymer | 71 | 8535.9 | 1 | UniProt (O15516) Pfam (PF00010) In PDB | Homo sapiens (human) | hCLOCK, Class E basic helix-loop-helix protein 8, bHLHe8 |
3 | C | E-box DNA sense strand | polymer | 15 | 4588.0 | 1 | |||
4 | D | E-box DNA antisense strand | polymer | 15 | 4592.0 | 1 | |||
5 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 66 - 128 (UniProt: O00327)
B: 29 - 89 (UniProt: O15516)
PDB | External Database | Details |
---|---|---|
Met 65 | - | expression tag |
Trp 129 | - | expression tag |
Leu 130 | - | expression tag |
Glu 131 | - | expression tag |
His 132 | - | expression tag |
His 133 | - | expression tag |
His 134 | - | expression tag |
His 135 | - | expression tag |
His 136 | - | expression tag |
His 137 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 28 | - | expression tag |
Trp 90 | - | expression tag |
Leu 91 | - | expression tag |
Glu 92 | - | expression tag |
His 93 | - | expression tag |
His 94 | - | expression tag |
His 95 | - | expression tag |
His 96 | - | expression tag |
His 97 | - | expression tag |
His 98 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 26409.0 | |
All* | Total formula weight | 26409.0 |