4H10

Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA

エンティティ

Entity ID	鎖名	説明	種類	鎖長	化学式量	分子数	データベース名(アクセス番号)	由来する生物種	エンティティの一般名
1	A	Aryl hydrocarbon receptor nuclear translocator-like protein 1	polymer	73	8693.2	1	UniProt (O00327) Pfam (PF00010) In PDB	Homo sapiens (human)	Basic-helix-loop-helix-PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5, bHLHe5, Member of PAS protein 3, PAS domain-containing protein 3, bHLH-PAS protein JAP3
2	B	Circadian locomoter output cycles protein kaput	polymer	71	8535.9	1	UniProt (O15516) Pfam (PF00010) In PDB	Homo sapiens (human)	hCLOCK, Class E basic helix-loop-helix protein 8, bHLHe8
3	C	E-box DNA sense strand	polymer	15	4588.0	1
4	D	E-box DNA antisense strand	polymer	15	4592.0	1
5		water	water		18.0	106	Chemie (HOH)

配列変更

A: 66 - 128 (UniProt: O00327)

PDB	外部データベース	詳細
Met 65	-	expression tag
Trp 129	-	expression tag
Leu 130	-	expression tag
Glu 131	-	expression tag
His 132	-	expression tag
His 133	-	expression tag
His 134	-	expression tag
His 135	-	expression tag
His 136	-	expression tag
His 137	-	expression tag

B: 29 - 89 (UniProt: O15516)

PDB	外部データベース	詳細
Met 28	-	expression tag
Trp 90	-	expression tag
Leu 91	-	expression tag
Glu 92	-	expression tag
His 93	-	expression tag
His 94	-	expression tag
His 95	-	expression tag
His 96	-	expression tag
His 97	-	expression tag
His 98	-	expression tag

非対称単位の内容

タンパク質・ 核酸鎖	鎖の数	4
	化学式量合計	26409.0
全て*	化学式量合計	26409.0

*水分子は含んでいません