3OS2

PFV target capture complex (TCC) at 3.32 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Integrase	polymer	395	44456.7	2	UniProt (P14350) Pfam (PF17921) Pfam (PF00665) Pfam (PF18103)	Human spumaretrovirus	Pr125Pol, Protease/Reverse transcriptase/ribonuclease H, p87Pro-RT-RNaseH, Protease/Reverse transcriptase, p65Pro-RT, Ribonuclease H, RNase H, Integrase, IN, p42In
2	C (C)	DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3')	polymer	19	5834.8	1
3	D (D)	DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3')	polymer	17	5195.4	1
4	E (T)	DNA (5'-D(*CP*CP*CP*GP*AP*GP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*CP*TP*CP*GP*GP*G)-3')	polymer	30	9226.9	1
5	F (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6	G (B)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)

Sequence modifications

A, B: 1 - 392 (UniProt: P14350)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag
Ser 217	Gly 968	SEE REMARK 999
Gly 218	Ser 969	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	109170.5
Non-Polymers*	Number of molecules	2
	Total formula weight	161.5
All*	Total formula weight	109332.0

*Water molecules are not included.