3J2T

An improved model of the human apoptosome

Replaces:  3IZAReplaces:  3IYT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Apoptotic protease-activating factor 1	polymer	1263	144095.8	7	UniProt (O14727) Pfam (PF00619) Pfam (PF00400) Pfam (PF00931) Pfam (PF21296) Pfam (PF17908) In PDB	Homo sapiens (human)	APAF-1
2	H, I, J, K, L...	Cytochrome c	polymer	104	11595.4	7	UniProt (P62894) Pfam (PF00034) In PDB	Bos taurus (bovine)
3	A, B, C, D, E...	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	7	Chemie (ATP)
4	M, N, H, I, J...	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	7	Chemie (HEM)

Sequence modifications

A, B, C, D, E, F, G: 1 - 1248 (UniProt: O14727)

PDB	External Database	Details
His -5	-	EXPRESSION TAG
His -4	-	EXPRESSION TAG
His -3	-	EXPRESSION TAG
His -2	-	EXPRESSION TAG
His -1	-	EXPRESSION TAG
His 0	-	EXPRESSION TAG
His 1249	-	EXPRESSION TAG
His 1250	-	EXPRESSION TAG
His 1251	-	EXPRESSION TAG
His 1252	-	EXPRESSION TAG
His 1253	-	EXPRESSION TAG
His 1254	-	EXPRESSION TAG
His 1255	-	EXPRESSION TAG
His 1256	-	EXPRESSION TAG
His 1257	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	1089838.4
Non-Polymers*	Number of molecules	14
	Total formula weight	7865.7
All*	Total formula weight	1097704.1

*Water molecules are not included.