3F8A
Crystal Structure of the R132K:R111L:L121E:R59W Mutant of Cellular Retinoic Acid-Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.95 Angstrom resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15554.7 | 1 | UniProt (P29373) Pfam (PF00061) In PDB | Homo sapiens (Human) | Cellular retinoic acid-binding protein II, CRABP-II |
| 2 | A | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 3 | A | 1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene | non-polymer | 204.4 | 1 | Chemie (LSR) | |||
| 4 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 1 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Trp 59 | Arg 60 | engineered mutation |
| Leu 111 | Arg 112 | engineered mutation |
| Glu 121 | Leu 122 | engineered mutation |
| Lys 132 | Arg 133 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15554.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 486.7 | |
| All* | Total formula weight | 16041.4 |
