2X7H

Crystal structure of the human MGC45594 gene product in complex with fenoprofen

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2	polymer	370	39475.2	2	UniProt (Q8N4Q0) Pfam (PF08240) Pfam (PF00107) In PDB	HOMO SAPIENS (HUMAN)	MGC45594 GENE PRODUCT
2	A, B	FENOPROFEN	non-polymer		242.3	6	Chemie (PFN)
3	A, B	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
4	A, B	1,2-ETHANEDIOL	non-polymer		62.1	13	Chemie (EDO)
5		water	water		18.0	413	Chemie (HOH)

Sequence modifications

A, B: 25 - 371 (UniProt: Q8N4Q0)

PDB	External Database	Details
Met 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Ser 9	-	expression tag
Ser 10	-	expression tag
Gly 11	-	expression tag
Val 12	-	expression tag
Asp 13	-	expression tag
Leu 14	-	expression tag
Gly 15	-	expression tag
Thr 16	-	expression tag
Glu 17	-	expression tag
Asn 18	-	expression tag
Leu 19	-	expression tag
Tyr 20	-	expression tag
Phe 21	-	expression tag
Gln 22	-	expression tag
Ser 23	-	expression tag
Met 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78950.4
Non-Polymers*	Number of molecules	21
	Total formula weight	3747.3
All*	Total formula weight	82697.7

*Water molecules are not included.