2J50
Structure of Aurora-2 in complex with PHA-739358
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | SERINE/THREONINE-PROTEIN KINASE 6 | polymer | 280 | 32369.1 | 2 | UniProt (O14965) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, AURORA-RELATED KINASE 1, HARK1, AURORA-A, BREAST-TUMOR-AMPLIFIED KINASE |
2 | A, B | N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE | non-polymer | 474.6 | 2 | Chemie (627) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 64738.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1141.2 | |
All* | Total formula weight | 65879.4 |