2C5X
Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33976.5 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | CYCLIN DEPENDENT KINASE 2, P33 PROTEIN KINASE |
2 | B, D | CYCLIN A2 | polymer | 259 | 29753.4 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | HOMO SAPIENS (HUMAN) | CYCLIN A |
3 | A, C | HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM | non-polymer | 373.4 | 2 | Chemie (MTW) | |||
4 | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 127459.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 746.7 | |
All* | Total formula weight | 128206.5 |