2XSN
Crystal Structure of Human Tyrosine Hydroxylase Catalytic Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | TYROSINE 3-MONOOXYGENASE | polymer | 343 | 39084.9 | 4 | UniProt (P07101) Pfam (PF00351) | HOMO SAPIENS (HUMAN) | TYROSINE 3-HYDROXYLASE, TH |
| 2 | E, F, G, H (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 193 - 528 (UniProt: P07101)
| PDB | External Database | Details |
|---|---|---|
| Met 193 | Lys 193 | engineered mutation |
| Ala 529 | - | expression tag |
| Glu 530 | - | expression tag |
| Asn 531 | - | expression tag |
| Leu 532 | - | expression tag |
| Tyr 533 | - | expression tag |
| Phe 534 | - | expression tag |
| Gln 535 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 156339.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 156601.2 |
