2I2R
Crystal structure of the KChIP1/Kv4.3 T1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, I... (A, B, C, D, I...) | Potassium voltage-gated channel subfamily D member 3 | polymer | 144 | 16807.0 | 8 | UniProt (Q62897) Pfam (PF11601) Pfam (PF02214) | Rattus norvegicus (Norway rat) | Voltage-gated potassium channel subunit Kv4.3 |
| 2 | E, F, G, H, M... (E, F, G, H, M...) | Kv channel-interacting protein 1 | polymer | 180 | 21029.6 | 8 | UniProt (Q9NZI2) Pfam (PF13833) Pfam (PF13499) | Homo sapiens (human) | KChIP1, A-type potassium channel modulatory protein 1, Potassium channel-interacting protein 1, Vesicle APC-binding protein |
| 3 | GA, HA, IA, JA, Q... (I, J, K, L, A...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | AA, BA, DA, EA, KA... (G, H, M, N, O...) | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) | |||
| 5 | CA, FA, W, Z (G, H, E, F) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) |
Sequence modifications
A, B, C, D, I, J, K, L: 2 - 143 (UniProt: Q62897)
E, F, G, H, M, N, O, P: 37 - 216 (UniProt: Q9NZI2)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | cloning artifact |
| Ala 1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Ala 160 | Lys 171 | engineered mutation |
| Ala 167 | Lys 178 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 302692.9 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 1256.5 | |
| All* | Total formula weight | 303949.4 |
