1XB7

X-ray structure of ERRalpha LBD in complex with a PGC-1alpha peptide at 2.5A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Steroid hormone receptor ERR1	polymer	247	27033.2	1	UniProt (P11474) Pfam (PF00104)	Homo sapiens (human)	Estrogen-related receptor, alpha; ERR-alpha; NR3B1; Estrogen receptor-like 1
2	B (P)	Peroxisome proliferator activated receptor gamma coactivator 1 alpha	polymer	12	1393.6	1	UniProt (Q9UBK2)		PPAR gamma coactivator-1 alpha, PPARGC-1 alpha, PGC-1 alpha, Ligand effect modulator-6
3	C (P)	IODIDE ION	non-polymer		126.9	1	Chemie (IOD)
4	D, E (A, P)	water	water		18.0	84	Chemie (HOH)

Sequence modifications

A: 290 - 519 (UniProt: P11474)

PDB	External Database	Details
Gly 273	-	expression tag
Ser 274	-	expression tag
Ser 275	-	expression tag
His 276	-	expression tag
His 277	-	expression tag
His 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
Leu 282	-	expression tag
Glu 283	-	expression tag
Val 284	-	expression tag
Leu 285	-	expression tag
Phe 286	-	expression tag
Gln 287	-	expression tag
Gly 288	-	expression tag
Pro 289	-	expression tag

P: 205 - 216 (UniProt: Q9UBK2)

PDB	External Database	Details
Ala 207	Cys 207	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28426.8
Non-Polymers*	Number of molecules	1
	Total formula weight	126.9
All*	Total formula weight	28553.7

*Water molecules are not included.