1M9O
NMR structure of the first Zinc Binding domain of Nup475/TTP/TIS11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tristetraproline | polymer | 77 | 8972.2 | 1 | UniProt (P22893) Pfam (PF00642) | Mus musculus (house mouse) | TTP, TIS11A protein, TIS11, ZFP-36, Growth factor-inducible nuclear protein NUP475, TPA induced sequence 11 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 5 - 77 (UniProt: P22893)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| His 3 | - | cloning artifact |
| Met 4 | - | cloning artifact |
| Lys 57 | Tyr 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 8972.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 9037.6 |
