1DKF
CRYSTAL STRUCTURE OF A HETERODIMERIC COMPLEX OF RAR AND RXR LIGAND-BINDING DOMAINS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN (RETINOID X RECEPTOR-ALPHA) | polymer | 233 | 25968.1 | 1 | UniProt (P28700) Pfam (PF00104) | Mus musculus (house mouse) | RXR-ALPHA |
| 2 | B (B) | PROTEIN (RETINOIC ACID RECEPTOR-ALPHA) | polymer | 235 | 26600.0 | 1 | UniProt (P10276) Pfam (PF00104) | Homo sapiens (human) | RAR-ALPHA |
| 3 | C (A) | OLEIC ACID | non-polymer | 282.5 | 1 | Chemie (OLA) | |||
| 4 | D (B) | 4-[(4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-[1,2']BINAPTHALENYL-7-CARBONYL)-AMINO]-BENZOIC ACID | non-polymer | 450.5 | 1 | Chemie (BMS) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 230 - 462 (UniProt: P28700)
| PDB | External Database | Details |
|---|---|---|
| Ala 318 | Phe 318 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52568.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 733.0 | |
| All* | Total formula weight | 53301.1 |
