1L9L
| GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ETHANOL, Granulysin, ... | Authors: | Anderson, D.H, Sawaya, M.R, Cascio, D, Ernst, W, Krensky, A, Modlin, R, Eisenberg, D. | Deposit date: | 2002-03-25 | Release date: | 2002-11-06 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (0.92 Å) | Cite: | Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism J.Mol.Biol., 325, 2002
|
|
3BQP
| |
5U85
| Murine saposin-D (SapD), open conformation | Descriptor: | Saposin-D | Authors: | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | Deposit date: | 2016-12-13 | Release date: | 2018-06-13 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of saposin D in an open conformation. J. Struct. Biol., 204, 2018
|
|
6VZ0
| |
5W7D
| Murine acyloxyacyl hydrolase (AOAH), S262A mutant | Descriptor: | 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Gorelik, A, Illes, K, Nagar, B. | Deposit date: | 2017-06-19 | Release date: | 2018-01-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the mammalian lipopolysaccharide detoxifier. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
4UEX
| |
5W7E
| Murine acyloxyacyl hydrolase (AOAH), S262A mutant, with dimyristoyl phosphatidylcholine | Descriptor: | (2S)-3-hydroxypropane-1,2-diyl ditetradecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acyloxyacyl hydrolase, ... | Authors: | Gorelik, A, Illes, K, Nagar, B. | Deposit date: | 2017-06-19 | Release date: | 2018-01-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal structure of the mammalian lipopolysaccharide detoxifier. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6VZD
| N-terminal domain of mouse surfactant protein B (K46E/R51E mutant) with bound lipid | Descriptor: | (7Z,19R,22R)-25-amino-22-hydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphapentacos-7-en-19-yl (9Z)-octadec-9-enoate, Pulmonary surfactant-associated protein B | Authors: | Rapoport, T.A, Bodnar, N.O. | Deposit date: | 2020-02-28 | Release date: | 2020-11-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Mechanism of Lamellar Body Formation by Lung Surfactant Protein B. Mol.Cell, 81, 2021
|
|
6VZE
| |
4DDJ
| |
5W7B
| Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Gorelik, A, Illes, K, Nagar, B. | Deposit date: | 2017-06-19 | Release date: | 2018-01-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the mammalian lipopolysaccharide detoxifier. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
3RFI
| |
3BQQ
| |
2DOB
| Crystal Structure of Human Saposin A | Descriptor: | CALCIUM ION, Proactivator polypeptide | Authors: | Prive, G.G, Ahn, V.E. | Deposit date: | 2006-04-28 | Release date: | 2006-07-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of saposins A and C. Protein Sci., 15, 2006
|
|
2RB3
| Crystal Structure of Human Saposin D | Descriptor: | GLYCEROL, Proactivator polypeptide, SULFATE ION | Authors: | Maier, T, Rossman, M, Saenger, W. | Deposit date: | 2007-09-18 | Release date: | 2008-04-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions. Structure, 16, 2008
|
|
4V2O
| Structure of saposin B in complex with chloroquine | Descriptor: | N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, SAPOSIN-B | Authors: | Zubieta, C, Lai, X, Doyle, R.P. | Deposit date: | 2014-10-13 | Release date: | 2015-12-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | The Lysosomal Protein Saposin B Binds Chloroquine. Chemmedchem, 11, 2016
|
|
7MBK
| |
6VYN
| N-terminal domain of mouse surfactant protein B with bound lipid, wild type | Descriptor: | (7Z,19R,22R)-25-amino-22-hydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphapentacos-7-en-19-yl (9Z)-octadec-9-enoate, Pulmonary surfactant-associated protein B | Authors: | Rapoport, T.A, Bodnar, N.O. | Deposit date: | 2020-02-27 | Release date: | 2020-11-25 | Last modified: | 2021-01-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mechanism of Lamellar Body Formation by Lung Surfactant Protein B. Mol.Cell, 81, 2021
|
|
1N69
| Crystal structure of human saposin B | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, SAPOSIN B | Authors: | Ahn, V.E, Faull, K.F, Whitelegge, J.P, Fluharty, A.L, Prive, G.G. | Deposit date: | 2002-11-08 | Release date: | 2003-01-07 | Last modified: | 2021-06-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of saposin B reveals a dimeric shell for lipid binding Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1QDM
| CRYSTAL STRUCTURE OF PROPHYTEPSIN, A ZYMOGEN OF A BARLEY VACUOLAR ASPARTIC PROTEINASE. | Descriptor: | PROPHYTEPSIN | Authors: | Kervinen, J, Tobin, G.J, Costa, J, Waugh, D.S, Wlodawer, A, Zdanov, A. | Deposit date: | 1999-05-19 | Release date: | 1999-07-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of plant aspartic proteinase prophytepsin: inactivation and vacuolar targeting. EMBO J., 18, 1999
|
|
5W7A
| Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS (low quality saposin domain) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ... | Authors: | Gorelik, A, Illes, K, Nagar, B. | Deposit date: | 2017-06-19 | Release date: | 2018-01-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the mammalian lipopolysaccharide detoxifier. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6W1B
| |
6SLR
| |
2GTG
| |
2QYP
| |