1BF6
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![BU of 1bf6 by Molmil](/molmil-images/mine/1bf6) | PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHOSPHOTRIESTERASE HOMOLOGY PROTEIN, ... | Authors: | Buchbinder, J.L, Stephenson, R.C, Scanlan, T.S, Fletterick, R.J. | Deposit date: | 1998-05-27 | Release date: | 1999-06-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family. Biochemistry, 37, 1998
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5CH9
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![BU of 5ch9 by Molmil](/molmil-images/mine/5ch9) | Gkap mutant B12 | Descriptor: | COBALT (II) ION, Phosphotriesterase | Authors: | Chen, L.-Q. | Deposit date: | 2015-07-10 | Release date: | 2015-09-09 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Active site loop architecture enhance the promiscuous PTE activity in lactonase from Geobacillus kaustophilus HTA426 To Be Published
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7P85
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![BU of 7p85 by Molmil](/molmil-images/mine/7p85) | |
4E3T
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![BU of 4e3t by Molmil](/molmil-images/mine/4e3t) | |
1DPM
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![BU of 1dpm by Molmil](/molmil-images/mine/1dpm) | THREE-DIMENSIONAL STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE WITH BOUND SUBSTRATE ANALOG DIETHYL 4-METHYLBENZYLPHOSPHONATE | Descriptor: | DIETHYL 4-METHYLBENZYLPHOSPHONATE, FORMIC ACID, PHOSPHOTRIESTERASE, ... | Authors: | Vanhooke, J.L, Benning, M.M, Raushel, F.M, Holden, H.M. | Deposit date: | 1996-02-13 | Release date: | 1997-08-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of the zinc-containing phosphotriesterase with the bound substrate analog diethyl 4-methylbenzylphosphonate. Biochemistry, 35, 1996
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1EYW
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![BU of 1eyw by Molmil](/molmil-images/mine/1eyw) | THREE-DIMENSIONAL STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE WITH BOUND SUBSTRATE ANALOG TRIETHYLPHOSPHATE | Descriptor: | 2-PHENYL-ETHANOL, PHOSPHOTRIESTERASE, TRIETHYL PHOSPHATE, ... | Authors: | Holden, H.M, Benning, M.M, Raushel, F.M, Hong, S.-B. | Deposit date: | 2000-05-09 | Release date: | 2000-12-20 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The binding of substrate analogs to phosphotriesterase. J.Biol.Chem., 275, 2000
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1EZ2
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![BU of 1ez2 by Molmil](/molmil-images/mine/1ez2) | THREE-DIMENSIONAL STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE WITH BOUND SUBSTRATE ANALOG DIISOPROPYLMETHYL PHOSPHONATE. | Descriptor: | METHYLPHOSPHONIC ACID DIISOPROPYL ESTER, PHOSPHOTRIESTERASE, ZINC ION | Authors: | Holden, H.M, Benning, M.M, Raushel, F.M, Hong, S.-B. | Deposit date: | 2000-05-09 | Release date: | 2000-12-20 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The binding of substrate analogs to phosphotriesterase. J.Biol.Chem., 275, 2000
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6JSS
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![BU of 6jss by Molmil](/molmil-images/mine/6jss) | Structure of Geobacillus kaustophilus lactonase, Y99P mutant | Descriptor: | FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ... | Authors: | Xue, B, Yew, W.S. | Deposit date: | 2019-04-08 | Release date: | 2020-04-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Directed Computational Evolution of Quorum-Quenching Lactonases from the Amidohydrolase Superfamily. Structure, 28, 2020
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6JSU
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![BU of 6jsu by Molmil](/molmil-images/mine/6jsu) | |
6JST
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![BU of 6jst by Molmil](/molmil-images/mine/6jst) | |
2D2J
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![BU of 2d2j by Molmil](/molmil-images/mine/2d2j) | OpdA from Agrobacterium radiobacter without inhibitor/product present at 1.75 A resolution | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, phosphotriesterase | Authors: | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | Deposit date: | 2005-09-09 | Release date: | 2005-09-20 | Last modified: | 2015-08-19 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
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2D2G
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![BU of 2d2g by Molmil](/molmil-images/mine/2d2g) | OpdA from Agrobacterium radiobacter with bound product dimethylthiophosphate | Descriptor: | COBALT (II) ION, O,O-DIMETHYL HYDROGEN THIOPHOSPHATE, phosphotriesterase | Authors: | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | Deposit date: | 2005-09-08 | Release date: | 2005-09-20 | Last modified: | 2015-08-19 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
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2D2H
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![BU of 2d2h by Molmil](/molmil-images/mine/2d2h) | OpdA from Agrobacterium radiobacter with bound inhibitor trimethyl phosphate at 1.8 A resolution | Descriptor: | COBALT (II) ION, TRIMETHYL PHOSPHATE, phosphotriesterase | Authors: | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | Deposit date: | 2005-09-09 | Release date: | 2005-09-20 | Last modified: | 2015-08-19 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
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2VC7
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![BU of 2vc7 by Molmil](/molmil-images/mine/2vc7) | Structural basis for natural lactonase and promiscuous phosphotriesterase activities | Descriptor: | (4S)-4-(decanoylamino)-5-hydroxy-3,4-dihydro-2H-thiophenium, 1,2-ETHANEDIOL, ARYLDIALKYLPHOSPHATASE, ... | Authors: | Elias, M, Dupuy, J, Merone, L, Mandrich, L, Moniot, S, Rochu, D, Lecomte, C, Rossi, M, Masson, P, Manco, G, Chabriere, E. | Deposit date: | 2007-09-19 | Release date: | 2008-04-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities. J.Mol.Biol., 379, 2008
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2VC5
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![BU of 2vc5 by Molmil](/molmil-images/mine/2vc5) | Structural basis for natural lactonase and promiscuous phosphotriesterase activities | Descriptor: | 1,2-ETHANEDIOL, ARYLDIALKYLPHOSPHATASE, COBALT (II) ION, ... | Authors: | Elias, M, Dupuy, J, Merone, L, Mandrich, L, Moniot, S, Lecomte, C, Rossi, M, Masson, P, Manco, G, Chabriere, E. | Deposit date: | 2007-09-18 | Release date: | 2008-04-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities. J.Mol.Biol., 379, 2008
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8UQZ
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![BU of 8uqz by Molmil](/molmil-images/mine/8uqz) | Round 18 Arylesterase Variant of Phosphotriesterase Bound to Gadolinium(III) Measured at 9.5 keV | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GADOLINIUM ION, ... | Authors: | Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J. | Deposit date: | 2023-10-25 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase. Acta Crystallogr D Struct Biol, 80, 2024
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8UQW
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![BU of 8uqw by Molmil](/molmil-images/mine/8uqw) | Round 18 Arylesterase Variant of Apo-Phosphotriesterase Measured at 13 keV | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphotriesterase variant PTE-R18 | Authors: | Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J. | Deposit date: | 2023-10-25 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase. Acta Crystallogr D Struct Biol, 80, 2024
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8UQY
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![BU of 8uqy by Molmil](/molmil-images/mine/8uqy) | Round 18 Arylesterase Variant of Phosphotriesterase Bound to Europium(III) Measured at 9.5 keV | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, EUROPIUM (III) ION, ... | Authors: | Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J. | Deposit date: | 2023-10-25 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase. Acta Crystallogr D Struct Biol, 80, 2024
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8UQX
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![BU of 8uqx by Molmil](/molmil-images/mine/8uqx) | Round 18 Arylesterase Variant of Apo-Phosphotriesterase Measured at 9.5 keV | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphotriesterase variant PTE-R18 | Authors: | Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J. | Deposit date: | 2023-10-25 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase. Acta Crystallogr D Struct Biol, 80, 2024
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4RE0
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![BU of 4re0 by Molmil](/molmil-images/mine/4re0) | Crystal structure of VmoLac in P622 space group | Descriptor: | COBALT (II) ION, GLYCEROL, MYRISTIC ACID, ... | Authors: | Hiblot, J, Bzdrenga, J, Champion, C, Gotthard, G, Gonzalez, D, Chabriere, E, Elias, M. | Deposit date: | 2014-09-20 | Release date: | 2015-02-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia. Sci Rep, 5, 2015
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1HZY
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![BU of 1hzy by Molmil](/molmil-images/mine/1hzy) | HIGH RESOLUTION STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE FROM PSEUDOMONAS DIMINUTA | Descriptor: | 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, FORMIC ACID, ... | Authors: | Holden, H.M, Benning, M.M, Raushel, F.M, Shim, H. | Deposit date: | 2001-01-26 | Release date: | 2001-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta. Biochemistry, 40, 2001
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1I0B
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![BU of 1i0b by Molmil](/molmil-images/mine/1i0b) | HIGH RESOLUTION STRUCTURE OF THE MANGANESE-CONTAINING PHOSPHOTRIESTERASE FROM PSEUDOMONAS DIMINUTA | Descriptor: | 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, FORMIC ACID, ... | Authors: | Holden, H.M, Benning, M.M, Raushel, F.M, Shim, H. | Deposit date: | 2001-01-29 | Release date: | 2001-04-04 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta. Biochemistry, 40, 2001
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1I0D
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![BU of 1i0d by Molmil](/molmil-images/mine/1i0d) | HIGH RESOLUTION STRUCTURE OF THE ZINC/CADMIUM-CONTAINING PHOSPHOTRIESTERASE FROM PSEUDOMONAS DIMINUTA | Descriptor: | 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, CADMIUM ION, ... | Authors: | Holden, H.M, Benning, M.M, Raushel, F.M, Shim, H. | Deposit date: | 2001-01-29 | Release date: | 2001-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta. Biochemistry, 40, 2001
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4RDZ
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![BU of 4rdz by Molmil](/molmil-images/mine/4rdz) | Crystal structure of VmoLac in P64 space group | Descriptor: | COBALT (II) ION, GLYCEROL, MYRISTIC ACID, ... | Authors: | Hiblot, J, Bzdrenga, J, Champion, C, Gotthard, G, Gonzalez, D, Chabriere, E, Elias, M. | Deposit date: | 2014-09-20 | Release date: | 2015-02-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia. Sci Rep, 5, 2015
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4QSF
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![BU of 4qsf by Molmil](/molmil-images/mine/4qsf) | CRYSTAL STRUCTURE of AMIDOHYDROLASE PMI1525 (TARGET EFI-500319) FROM PROTEUS MIRABILIS HI4320, A COMPLEX WITH BUTYRIC ACID AND MANGANESE | Descriptor: | Amidohydrolase Pmi1525, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Patskovsky, Y, Toro, R, Xiang, D.F, Raushel, F.M, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-07-03 | Release date: | 2014-07-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structure of Amidohydrolase Pmi1525 from Proteus Mirabilis Hi4320 To be Published
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