1AM4
  • Download 1am4
  • View 1am4
Molmil generated image of 1am4
COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS)
Descriptor:P50-RHOGAP, CDC42HS, MAGNESIUM ION, ...
Authors:Rittinger, K., Walker, P., Gamblin, S.J., Smerdon, S.J.
Deposit date:1997-06-22
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
Nature, 388, 1997
1F7C
  • Download 1f7c
  • View 1f7c
Molmil generated image of 1f7c
CRYSTAL STRUCTURE OF THE BH DOMAIN FROM GRAF, THE GTPASE REGULATOR ASSOCIATED WITH FOCAL ADHESION KINASE
Descriptor:RHOGAP PROTEIN
Authors:Longenecker, K.L., Derewenda, U., Sheffield, P.J., Zheng, Y., Derewenda, Z.S.
Deposit date:2000-06-26
Release date:2000-12-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the BH domain from graf and its implications for Rho GTPase recognition.
J.Biol.Chem., 275, 2000
1PBW
  • Download 1pbw
  • View 1pbw
Molmil generated image of 1pbw
STRUCTURE OF BCR-HOMOLOGY (BH) DOMAIN
Descriptor:PHOSPHATIDYLINOSITOL 3-KINASE
Authors:Musacchio, A., Cantley, L.C., Harrison, S.C.
Deposit date:1996-10-17
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit.
Proc.Natl.Acad.Sci.USA, 93, 1996
1RGP
  • Download 1rgp
  • View 1rgp
Molmil generated image of 1rgp
GTPASE-ACTIVATION DOMAIN FROM RHOGAP
Descriptor:RHOGAP
Authors:Barrett, T., Xiao, B., Dodson, E.J., Dodson, G., Ludbrook, S.B., Nurmahomed, K., Gamblin, S.J., Musacchio, A., Smerdon, S.J., Eccleston, J.F.
Deposit date:1996-12-05
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the GTPase-activating domain from p50rhoGAP.
Nature, 385, 1997
1TX4
  • Download 1tx4
  • View 1tx4
Molmil generated image of 1tx4
RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
Descriptor:P50-RHOGAP, TRANSFORMING PROTEIN RHOA, MAGNESIUM ION, ...
Authors:Rittinger, K., Walker, P.A., Smerdon, S.J., Gamblin, S.J.
Deposit date:1997-07-29
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
Nature, 389, 1997
2EE4
  • Download 2ee4
  • View 2ee4
Molmil generated image of 2ee4
SOLUTION STRUCTURE OF THE RHOGAP DOMAIN FROM HUMAN RHO GTPASE ACTIVATING PROTEIN 5 VARIANT
Descriptor:Rho GTPase activating protein 5 variant
Authors:Tomizawa, T., Tochio, N., Koshiba, S., Watanabe, S., Harada, T., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-15
Release date:2007-08-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant
To be Published
2EE5
  • Download 2ee5
  • View 2ee5
Molmil generated image of 2ee5
SOLUTION STRUCTURE OF THE N-TERUMINUS EXTENDED RHOGAP DOMAIN FROM HUMAN RHO GTPASE ACTIVATING PROTEIN 5 VARIANT
Descriptor:Rho GTPase activating protein 5 variant
Authors:Tomizawa, T., Tochio, N., Koshiba, S., Watanabe, S., Harada, T., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-15
Release date:2007-08-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the N-teruminus extended RhoGAP domain from human Rho GTPase activating protein 5 variant
To be Published
2MBG
  • Download 2mbg
  • View 2mbg
Molmil generated image of 2mbg
RLIP76 (GAP-GBD)
Descriptor:RalA-binding protein 1
Authors:Rajasekar, K.V., Campbell, L.J., Nietlispach, D., Owen, D., Mott, H.R.
Deposit date:2013-07-30
Release date:2013-12-04
Last modified:2013-12-25
Method:SOLUTION NMR
Cite:The Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the Membrane.
Structure, 21, 2013
2OSA
  • Download 2osa
  • View 2osa
Molmil generated image of 2osa
THE RHO-GAP DOMAIN OF HUMAN N-CHIMAERIN
Descriptor:N-chimaerin
Authors:Walker, J.R., Hong, B.S., Shen, L., Arrowsmith, C.H., Sundstrom, M., Weigelt, J., Edwards, A.M., Bochkarev, A., Park, H.W., Structural Genomics Consortium (SGC)
Deposit date:2007-02-05
Release date:2007-03-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Rho-GAP domain from human N-chimaerin
To be Published
2OVJ
  • Download 2ovj
  • View 2ovj
Molmil generated image of 2ovj
THE CRYSTAL STRUCTURE OF THE HUMAN RAC GTPASE ACTIVATING PROTEIN 1 (RACGAP1) MGCRACGAP.
Descriptor:Rac GTPase-activating protein 1, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL
Authors:Shrestha, L., Papagrigoriou, E., Soundararajan, M., Elkins, J., Johansson, C., von Delft, F., Pike, A.C.W., Burgess, N., Turnbull, A., Debreczeni, J., Gorrec, F., Umeano, C., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-02-14
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP.
To be Published
2QV2
  • Download 2qv2
  • View 2qv2
Molmil generated image of 2qv2
A ROLE OF THE LOWE SYNDROME PROTEIN OCRL IN EARLY STEPS OF THE ENDOCYTIC PATHWAY
Descriptor:Inositol polyphosphate 5-phosphatase OCRL-1
Authors:Mao, Y., Erdman, K.S., McCrea, H.J., De Camilli, P.
Deposit date:2007-08-07
Release date:2007-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway
Dev.Cell, 13, 2007
2XS6
  • Download 2xs6
  • View 2xs6
Molmil generated image of 2xs6
CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2
Descriptor:PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA, CHLORIDE ION
Authors:Tresaugues, L., Welin, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Moche, M., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., van der Berg, S., Wahlberg, E., Weigelt, J., Nordlund, P.
Deposit date:2010-09-24
Release date:2010-11-17
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The Structure and Catalytic Mechanism of Human Sphingomyelin Phosphodiesterase Like 3A - an Acid Sphingomyelinase Homolog with a Novel Nucleotide Hydrolase Activity.
FEBS J., 283, 2016
3BYI
  • Download 3byi
  • View 3byi
Molmil generated image of 3byi
CRYSTAL STRUCTURE OF HUMAN RHO GTPASE ACTIVATING PROTEIN 15 (ARHGAP15)
Descriptor:Rho GTPase activating protein 15
Authors:Shrestha, L., Tickle, J., Elkins, J., Burgess-Brown, N., Johansson, C., Papagrigoriou, E., Kavanagh, K., Pike, A.C.W., Ugochukwu, E., Uppenberg, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2008-01-16
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Human Rho GTPase Activating Protein 15 (ARHGAP15).
To be Published
3EAP
  • Download 3eap
  • View 3eap
Molmil generated image of 3eap
CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF ARHGAP11A
Descriptor:Rho GTPase-activating protein 11A, UNKNOWN ATOM OR ION
Authors:Shen, Y., Shen, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium, Structural Genomics Consortium (SGC)
Deposit date:2008-08-26
Release date:2008-09-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the RhoGAP domain of ARHGAP11A
To be Published
3FK2
  • Download 3fk2
  • View 3fk2
Molmil generated image of 3fk2
CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN GLUCOCORTICOID RECEPTOR DNA-BINDING FACTOR 1
Descriptor:Glucocorticoid receptor DNA-binding factor 1, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L., Tong, Y., Tempel, W., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2008-12-15
Release date:2008-12-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1
To be Published
3IUG
  • Download 3iug
  • View 3iug
Molmil generated image of 3iug
CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF RICS
Descriptor:Rho/Cdc42/Rac GTPase-activating protein RICS, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L., Tempel, W., Tong, Y., Li, Y., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2009-08-31
Release date:2009-09-29
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of the RhoGAP domain of RICS
to be published
3KUQ
  • Download 3kuq
  • View 3kuq
Molmil generated image of 3kuq
CRYSTAL STRUCTURE OF THE DLC1 RHOGAP DOMAIN
Descriptor:Rho GTPase-activating protein 7, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L., Tempel, W., Tong, Y., MacKenzie, F., Shen, L., Zhong, N., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2009-11-27
Release date:2010-01-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the DLC1 RhoGAP domain
to be published
3QIS
  • Download 3qis
  • View 3qis
Molmil generated image of 3qis
RECOGNITION OF THE F&H MOTIF BY THE LOWE SYNDROME PROTEIN OCRL
Descriptor:Inositol polyphosphate 5-phosphatase OCRL-1, Protein FAM109A
Authors:Pirruccello, M., Swan, L.E., Folta-Stogniew, E., De Camilli, P.
Deposit date:2011-01-27
Release date:2011-06-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recognition of the F&H motif by the Lowe syndrome protein OCRL.
Nat.Struct.Mol.Biol., 18, 2011
3W6R
  • Download 3w6r
  • View 3w6r
Molmil generated image of 3w6r
CRYSTAL STRUCTURE OF THE GAP DOMAIN OF HUMAN MGCRACGAP
Descriptor:Rac GTPase-activating protein 1
Authors:Matsuura, A., Lee, H.H.
Deposit date:2013-02-21
Release date:2014-02-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of GTPase-activating domain from human MgcRacGAP.
Biochem.Biophys.Res.Commun., 435, 2013
3WPQ
  • Download 3wpq
  • View 3wpq
Molmil generated image of 3wpq
CRYSTAL STRUCTURE OF THE GAP DOMAIN OF MGCRACGAP(S387A)
Descriptor:Rac GTPase-activating protein 1
Authors:Murayama, K., Kato-Murayama, M., Shirouzu, M., Kitamura, T., Yokoyama, S.
Deposit date:2014-01-15
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:crystal structure of the GAP domain of MgcRacGAP
To be Published
3WPS
  • Download 3wps
  • View 3wps
Molmil generated image of 3wps
CRYSTAL STRUCTURE OF THE GAP DOMAIN OF MGCRACGAP(S387D)
Descriptor:Rac GTPase-activating protein 1, SULFATE ION
Authors:Murayama, K., Kato-murayama, M., Shirouzu, M., Kitamura, T., Yokoyama, S.
Deposit date:2014-01-15
Release date:2015-01-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:crystal structure of the GAP domain of MgcRacGAP
To be Published
5C5S
  • Download 5c5s
  • View 5c5s
Molmil generated image of 5c5s
CRYSTAL STRUCTURE OF HUMAN MYOSIN 9B RHOGAP DOMAIN AT 2.2 ANGSTROM
Descriptor:Unconventional myosin-IXb
Authors:Yi, F.S., Ren, J.Q., Feng, W.
Deposit date:2015-06-22
Release date:2015-11-25
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression
J.Clin.Invest., 125, 2015
5JD0
  • Download 5jd0
  • View 5jd0
Molmil generated image of 5jd0
CRYSTAL STRUCTURE OF ARAP3 RHOGAP DOMAIN
Descriptor:Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Bao, H., Li, F., Wu, J., Shi, Y.
Deposit date:2016-04-15
Release date:2016-06-22
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3
J.Biol.Chem., 291, 2016
5MY3
  • Download 5my3
  • View 5my3
Molmil generated image of 5my3
CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF RGD1P AT 2.19 ANGSTROMS RESOLUTION
Descriptor:RHO GTPase-activating protein RGD1
Authors:Martinez, D.M., d'Estaintot, B.L., Granier, T., Hugues, M., Odaert, B., Gallois, B., Doignon, F.
Deposit date:2017-01-25
Release date:2018-01-24
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural evidence of a phosphoinositide-binding site in the Rgd1-RhoGAP domain.
Biochem. J., 474, 2017
6D81
  • Download 6d81
  • View 6d81
Molmil generated image of 6d81
STRUCTURE OF THE BOVINE P85A BH DOMAIN
Descriptor:Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION
Authors:Moore, S.A., Marshall, J.D., Anderson, D.H.
Deposit date:2018-04-25
Release date:2018-05-23
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8, 2018
<12>
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2018 Protein Data Bank Japan