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1RG8
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Human Acidic Fibroblast Growth Factor (haFGF-1) at 1.10 angstrom resolution (140 amino acid form)
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Bernett, M.J, Somasundaram, T, Blaber, M.
Deposit date:2003-11-11
Release date:2004-10-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:An atomic resolution structure for human fibroblast growth factor 1.
Proteins, 57, 2004
1PWA
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Crystal structure of Fibroblast Growth Factor 19
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ...
Authors:Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L.
Deposit date:2003-07-01
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.
Biochemistry, 43, 2004
8OM6
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Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2
Descriptor: Fibroblast growth factor 2
Authors:Marek, M, Chaloupkova, R, de La Bourdonnaye, G.
Deposit date:2023-03-31
Release date:2024-03-06
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2
To Be Published
8HU7
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Crystal structure of FGF2-M1 mutant - D28E/C78L/C96I/S137P
Descriptor: Fibroblast growth factor 2
Authors:Jung, Y.E, Cha, S.S, An, Y.J.
Deposit date:2022-12-22
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of FGF2-M1 mutant - D28E/C78L/C96I/S137P
To Be Published
2J3P
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crystal structure of rat FGF1 at 1.4 A
Descriptor: HEPARIN-BINDING GROWTH FACTOR 1, SULFATE ION
Authors:Kulahin, N, Kristensen, O, Berezin, V, Gajhede, M, Bock, E.
Deposit date:2006-08-22
Release date:2007-02-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of Rat Acidic Fibroblast Growth Factor at 1.4 A Resolution.
Acta Crystallogr.,Sect.F, 63, 2007
8HUE
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Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 2
Authors:Jung, Y.E, Cha, S.S, An, Y.J.
Deposit date:2022-12-23
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P
To Be Published
4QC4
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Crystal structure of C117S mutant of human acidic fibroblast growth factor
Descriptor: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE, ...
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-09
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QBV
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Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium citrate buffer
Descriptor: CITRATE ANION, Fibroblast growth factor 1
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-08
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
2P39
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Crystal structure of human FGF23
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 23
Authors:Mohammadi, M.
Deposit date:2007-03-08
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
3BB2
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Crystal structure of L26D/D28N mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-09
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
4OEE
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Crystal Structure Analysis of FGF2-Disaccharide (S3I2) complex
Descriptor: 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Fibroblast growth factor 2
Authors:Li, Y.C, Hsiao, C.D.
Deposit date:2014-01-13
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
Acs Chem.Biol., 9, 2014
4QAL
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Crystal structure of C117A mutant of human acidic fibroblast growth factor
Descriptor: CITRATE ANION, Fibroblast growth factor 1
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4QBC
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BU of 4qbc by Molmil
Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium formate buffer
Descriptor: FORMIC ACID, Fibroblast growth factor 1, SULFATE ION
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-07
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.519 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
3BAO
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Crystal structure of L26N mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3B9U
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BU of 3b9u by Molmil
Crystal structure of L26N/D28N/H93G mutant of Human acidic fibroblast growth factor
Descriptor: Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2007-11-06
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
4Q9G
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BU of 4q9g by Molmil
Crystal structure of K12V/C16S/C117V/P134V mutant of human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Fibroblast growth factor 1, PHOSPHATE ION
Authors:Blaber, M, Xia, X.
Deposit date:2014-05-01
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.554 Å)
Cite:Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
2HW9
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BU of 2hw9 by Molmil
Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution.
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
4OEG
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BU of 4oeg by Molmil
Crystal Structure Analysis of FGF2-Disaccharide (S9I2) complex
Descriptor: 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Fibroblast growth factor 2
Authors:Li, Y.C, Hsiao, C.D.
Deposit date:2014-01-13
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
Acs Chem.Biol., 9, 2014
1BFG
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BU of 1bfg by Molmil
CRYSTAL STRUCTURE OF BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION
Descriptor: BASIC FIBROBLAST GROWTH FACTOR
Authors:Kitagawa, Y, Ago, H, Katsube, Y, Fujishima, A, Matsuura, Y.
Deposit date:1993-04-15
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of basic fibroblast growth factor at 1.6 A resolution.
J.Biochem.(Tokyo), 110, 1991
4FGF
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BU of 4fgf by Molmil
REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
Descriptor: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SULFATE ION
Authors:Eriksson, A.E, Matthews, B.W.
Deposit date:1993-02-26
Release date:1993-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Protein Sci., 2, 1993
2HWM
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BU of 2hwm by Molmil
Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2006-08-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
1P63
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BU of 1p63 by Molmil
Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I)
Descriptor: ACIDIC FIBROBLAST GROWTH FACTOR, FORMIC ACID, SULFATE ION
Authors:Brych, S.R, Kim, J, Logan, T.M, Blaber, M.
Deposit date:2003-04-28
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
3BAU
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BU of 3bau by Molmil
Crystal structure of K12V/L26D/D28A mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J, Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BA7
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BU of 3ba7 by Molmil
Crystal structure of L26N/D28A mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3O3Q
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Crystal structure of "L44F/M67I/L73V/A103G/deletion 104-106/F108Y/V109L/L111I/C117V/R119G/deletion 120-122" mutant form of Human acidic fibroblast growth factor
Descriptor: GLYCEROL, Heparin-binding growth factor 1
Authors:Lee, J, Blaber, M.
Deposit date:2010-07-25
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A polypeptide "building block"top-down symmetric deconstruction".
J.Mol.Biol., 407, 2011

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